Cardiovascular Pathology - Case 2 - Part 3
   

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The patient was treated with surgical resection of ischemic bowel on 8-18-03 when free air was found on abdominal films. Pathologic review of the surgical material did not find evidence for active PAN. The patient developed fevers on the second postoperative day and it was thought that he had developed an anastomic leak in the bowel and sepsis. He was given comfort measures and died on 8-21-03. An Autopsy was requested.

CXR from 8-19-03
CXR from 8-21-03
CBC with Differential

Name

Result/Unit

 

Ref Interval

WHITE BLOOD CELL COUNT

4.15 K/uL

 

3.20-10.60

RED BLOOD CELL COUNT

2.20 M/uL

L

4.69-6.07

HEMOGLOBIN

7.9 g/dL

L

14.6-17.8

HEMATOCRIT

22.5 %

L

40.8-51.9

MEAN CORPUSCULAR VOLUME

102.4 fL

H

77.8-94.0

MEAN CORPUSCULAR HEMOGLOBIN

36.1 pg

H

26.5-32.6

MEAN CORPUSCULAR HGB CONC

35.2 g/dL

 

32.7-36.9

RED CELL DISTRIBUTION WIDTH

18.0 %

H

10.8-14.1

PLATELETS

379 K/uL

 

177-406

MEAN PLATELET VOLUME

8.1 fL

 

5.9-9.8

POLYMORPHONUCLEAR

72 %

 

44-76

BAND

25 %

H

0-5

LYMPHOCYTE

2 %

L

15-43

EOSINOPHIL

1 %

 

0-6

PLATELET ESTIMATE

ADEQUATE

 

NORMAL

ANISOCYTOSIS

2+

A

 

POIKILOCYTOSIS

1+

A

 

MACROCYTOSIS

1+

A

 

POLYCHROMASIA

1+

A

 

SMEAR INTERPRETATION Comments:

PERIPHERAL BLOOD:
    - NORMOCHROMIC, MACROCYTIC ANEMIA WITH MODERATE ANISOPOIKILOCYTOSIS.
    - RELATIVE NEUTROPHILIA WITH SHIFT TO IMMATURITY IN MYELOID SERIES.
    - ABSOLUTE LYMPHOPENIA.

1. What do these CBC findings have to do with his underlying vasculitis?

2. What changes are seen on CXR?