Cardiovascular Pathology - Case 4 - Part 1
   

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The patient is a 62 year old male with a history of asbestos exposure and interstitial lung disease diagnosed in 1995. He has been on steroids since then and is currently on home O2 at 12 L. He was recently treated for pneumonia and is on the lung transplant list. He presents today with severe shortness of breath and is admitted to the hospital to the pulmonary service for intubation and mechanical ventilation.

Urinalysis

Result/Unit

 

Ref Interval

URINE COLLECTION

NOT SPEC

 

 

URINE COLOR

YELLOW

 

 

URINE APPEARANCE

CLOUDY

A

 

SPECIFIC GRAVITY, URINE

1.018

 

1.003-1.030

pH, URINE

5.0

 

5.0-7.5

URINE PROTEIN

NEG

 

NEG

URINE GLUCOSE

NEG

 

NEG

URINE KETONES

NEG

 

NEG

URINE BILIRUBIN

NEG

 

NEG

URINE BLOOD

SMALL

A

NEG

URINE NITRITE

NEG

 

NEG

URINE WBC SCREEN

NEG

 

NEG

URINE RBC/HPF

2-5 /HPF

 

0-5/HPF

URINE UROBILINOGEN

0.2 mg/dL

 

0.2-1.0

UR URIC ACID CRYSTALS

MANY

A

 

Blood Gas

Result/Unit

 

Ref Interval

FiO2

15 L

 

 

pH

7.439

 

7.35-7.45

PaCO2

29.1 mmHg

L

35-39

PaO2

52.7 mmHg

L

61-82

COHb

0.7 %

 

0.1-2

MethHb

0.9 %

 

0.1-2

tHb

16.6 gm%

 

13-19

O2 Content

19.4 vol%

 

17-24

Pb

638 mmHg

 

 

HCO3

19.4 mEq/L

 

19-25

BE

-2.9 mEq/L

L

-2.5-2.5

O2Hb

83.4 %

L

92-99

Temp

37 C

 

 

Allen`s Test

+

 

 

Name

Result/Unit

 

Ref Interval

PROTHROMBIN TIME

31.0 sec

H

12.0-15.5

INTERNATIONAL NORMALIZED RATIO

3.0 ratio

 

 

Name

Result/Unit

 

Ref Interval

SODIUM

132 mmol/L

L

136-144

POTASSIUM

5.8 mmol/L

H

3.3-5.0

CHLORIDE

96 mmol/L

L

98-107

CARBON DIOXIDE

18 mmol/L

L

22-29

UREA NITROGEN

34 mg/dL

H

9-22

CREATININE, SERUM - mg/dL

1.9 mg/dL

H

0.8-1.5

GLUCOSE

99 mg/dL

 

64-128

ANION GAP

18 mmol/L

H

8-14

CALCIUM, SERUM OR PLASMA

8.8 mg/dL

 

8.4-10.2

CBC with Dif

Result/Unit

 

Ref Interval

WHITE BLOOD CELL COUNT

29.64 K/uL

H

3.20-10.60

RED BLOOD CELL COUNT

5.39 M/uL

 

4.69-6.07

HEMOGLOBIN

16.8 g/dL

 

14.6-17.8

HEMATOCRIT

49.3 %

 

40.8-51.9

MEAN CORPUSCULAR VOLUME

91.5 fL

 

77.8-94.0

MEAN CORPUSCULAR HEMOGLOBIN

31.2 pg

 

26.5-32.6

MEAN CORPUSCULAR HGB CONC

34.1 g/dL

 

32.7-36.9

RED CELL DISTRIBUTION WIDTH

17.9 %

H

10.8-14.1

PLATELETS

301 K/uL

 

177-406

MEAN PLATELET VOLUME

8.9 fL

 

5.9-9.8

GRANULOCYTES %

86.6 %

H

44.0-76.0

MONOCYTE %

6.6 %

 

2.0-7.5

EOSINOPHIL %

0.3 %

 

0.0-6.0

AUTOMATED BASOPHIL %

1.2 %

 

0.0-1.7

GRANULOCYTE #

25.7 K/uL

H

1.3-7.0

MONOCYTE #

2.0 K/uL

H

.1-.5

AUTOMATED ABS EOSINOPHIL COUNT

0.1 K/uL

 

0.0-0.4

BASOPHILE #

0.3 K/uL

H

0.0-0.1

LYMPH #

1.6 K/uL

 

.8-3.1

LYMPHOCYTE %

5.3 %

L

14.7-42.6

1. What are the cardiac causes of shortness of breath?

2. How does lung disease affect the heart?

3. Review the admission laboratory results how did these help rule out the possibility of a pulmonary embolus?

EKG

4. What do you see on his EKG?

5. What is your differential diagnosis?