Cardiovascular Pathology - Case 8 - Part 1
   

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The patient is a 22 year old Hispanic male with little past medical history. He developed a cough in late February. It progressed to vomiting which resulted in admission on 3-18-03 for rehydration and an initial diagnosis of gastroenteritis was made. His symptoms worsened. A chest/abdomen CT scan was performed revealing a right upper lobe cavitary lesion suggestive of septic emboli to the lung. An echo revealed mitral valve vegetations and the patient was started on antibiotics.

The patient was neurologically intact on 3-18-03 but by 3-20-03 was complaining of photophobia and had dimming of his vision with blurring. By the next day he was entirely blind and he lost speech. On 3-25-03 he lost the use of his entire right side and on 4-3-03 he lost the use of his left side and his ability to swallow. Because of the extent of his disease he was transferred to this hospital on 4-4-03.

Name

Result/Unit

 

Ref Interval

PTT 1:1 MIX

28 sec

 

26-37

PROTHROMBIN TIME

18.8 sec

H

12.0-15.5

INTERNATIONAL NORMALIZED RATIO

1.6 ratio

 

 

PARTIAL THROMBOPLASTIN TIME

41 sec

H

26-37

FIBRINOGEN

118 mg/dL

L

150-430

D-DIMER

36.6 ug/mL

H

0.0-0.5

CBC

Result/Unit

 

Ref Interval

WHITE BLOOD CELL COUNT

27.47 K/uL

H

3.20-10.60

RED BLOOD CELL COUNT

3.67 M/uL

L

4.69-6.07

HEMOGLOBIN

11.5 g/dL

L

14.6-17.8

HEMATOCRIT

32.1 %

L

40.8-51.9

MEAN CORPUSCULAR VOLUME

87.5 fL

 

77.8-94.0

MEAN CORPUSCULAR HEMOGLOBIN

31.2 pg

 

26.5-32.6

MEAN CORPUSCULAR HGB CONC

35.7 g/dL

 

32.7-36.9

RED CELL DISTRIBUTION WIDTH

14.5 %

H

10.8-14.1

PLATELETS

69 K/uL

L

177-406

MEAN PLATELET VOLUME

8.2 fL

 

5.9-9.8

BMP

Result/Unit

 

Ref Interval

SODIUM

126 mmol/L

L

136-144

POTASSIUM

4.5 mmol/L

 

3.3-5.0

CHLORIDE

96 mmol/L

L

98-107

CARBON DIOXIDE

24 mmol/L

 

22-29

UREA NITROGEN

33 mg/dL

H

9-22

CREATININE, SERUM - mg/dL

1.1 mg/dL

 

0.8-1.5

GLUCOSE

93 mg/dL

 

64-128

ANION GAP

6 mmol/L

L

8-14

CALCIUM, SERUM OR PLASMA

8.5 mg/dL

 

8.4-10.2

Chest X-Ray from 4-4-03

1. What is your differential diagnosis?

2. Review the Chest film from 4-4-03 on admission. Are there any abnormalities?

3. Review the labs from 4-4-03. Are there any clues to his illness?