You are here: Home Education Residency Program Resident Research Resident Publications
Document Actions

Resident Publications

Up one level

Current Research publications by Department of Pathology Residents

Archana Mishra Agarwal, M.D.

  • Bruchova H, Yoon D, Agarwal AM, Mendell J, Prchal JT. Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Exp Hematol. 2007 Nov;35(11):1657-67.
  • Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, Caparros E, Buteau J, Brown K, Perkins SL, Bhagat G, Agarwal AM, Basso G, Castillo M, Nagase S, Cordon-Cardo C, Parsons R, Zúñiga-Pflücker JC, Dominguez M, Ferrando AA. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med. 2007 Oct;13(10):1203-10.
  • Agarwal AM, Agarwal N, Glenn MJ, Lim MS. Blastic transformation of low-grade follicular lymphoma. J Clin Oncol. 2007 Jun 1;25(16):2326-8.
  • Agarwal N, Tepe EM, Mishra A, Ward JH. Relapse of acute promyelocytic leukemia presenting as granulocytic sarcoma in the hip. Ann Hematol. 2006 Oct;85(10):741-2.
  • Gilbert-Barness E, Oostra RJ, Agarwal A, Zhou H, Opitz JM. Segmentation anomalies of vertebrae and ribs with other abnormalities of blastogenesis: syndromes or associations? Fetal Pediatr Pathol. 2005 Nov-Dec;24(6):331-45.
  • Chaudhary A, Mishra A, Sethi S. Oxidized omega-3 fatty acids inhibit pro-inflammatory responses in glomerular endothelial cells. Nephron Exp Nephrol. 2004;97(4):e136-45.
  • Mishra A, Chaudhary A, Sethi S. Oxidized omega-3 fatty acids inhibit NF-kappaB activation via a PPARalpha-dependent pathway. Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1621-7.
  • Nigam S, Singh T, Mishra A, Chaturvedi KU. Oral cysticercosis--report of six cases. Head Neck. 2001 Jun;23(6):497-9.

Heather M. Carney, M.D.

  • Emerson LL, Carney HM, Layfield LJ, Sherbotie JR. Collecting duct carcinoma arising in association with BK nephropathy post-transplantation in a pediatric patient. A case report with immunohistochemical and in situ hybridization study. Pediatr Transplant. 2008 Aug;12(5):600-5.
  • Werner TL, Agarwal N, Carney HM, Rodgers GM. Management of cancer-associated thrombotic microangiopathy: what is the right approach? Am J Hematol. 2007 Apr;82(4):295-8. Review.

Allie H. Grossmann, M.D., Ph.D.

  • Grossmann AH, Kolibaba KS, Willis SG, Corbin AS, Langdon WS, Deininger MW, Druker BJ. Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl. FEBS Lett. 2004 Nov 19;577(3):555-62.
  • Gurtu VE, Verma S, Grossmann AH, Liskay RM, Skarnes WC, Baker SM. Maternal effect for DNA mismatch repair in the mouse. Genetics. 2002 Jan;160(1):271-7.
  • Baker SM, Harris AC, Tsao JL, Flath TJ, Bronner CE, Gordon M, Shibata D, Liskay RM. Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice. Cancer Res. 1998 Mar 15;58(6):1087-9.
  • Prolla TA, Baker SM, Harris AC, Tsao JL, Yao X, Bronner CE, Zheng B, Gordon M, Reneker J, Arnheim N, Shibata D, Bradley A, Liskay RM. Abstract Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair. Nat Genet. 1998 Mar;18(3):276-9.
  • Baker SM, Plug AW, Prolla TA, Bronner CE, Harris AC, Yao X, Christie DM, Monell C, Arnheim N, Bradley A, Ashley T, Liskay RM. Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over. Nat Genet. 1996 Jul;13(3):336-42.

Brent J. Huddleston, M.D.

  • Mehta LR, Huddleston BJ, Skalabrin EJ, Burns JB, Zou WQ, Gambetti P, Chin SS. Sporadic Fatal Insomnia Masquerading as a Paraneoplastic Cerebellar Syndrome. Arch Neurol. 2008 Jul;65(7):971-973.
  • Huddleston BJ, Frank, EL; Clinical Chemistry, ASCP CheckSample, June 2008, Vol 48, No 4

Attila Kumanovics, M.D.

  • Kumánovics A, Chen OS, Li L, Bagley D, Adkins EM, Lin H, Dingra NN, Outten CE, Keller G, Winge D, Ward DM, Kaplan J. Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis. J Biol Chem. 2008 Apr 18;283(16):10276-86.
  • Kumanovics A. (2007). Genomic organization of the mouse MHC. In Fox JG, Barthold SW, Davisson MT, Newcomer CE, Smith AL, Quimby FW (Ed.), The Mouse in Biomedical Research, Volume 4: Immunology (pp. 119-134). MA: Academic Press.
  • Kumánovics A, Poruk KE, Osborn KA, Ward DM, Kaplan J. YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae. J Biol Chem. 2006 Aug 11;281(32):22566-74.
  • Dijkstra JM, Kiryu I, Yoshiura Y, Kumánovics A, Kohara M, Hayashi N, Ototake M. Polymorphism of two very similar MHC class Ib loci in rainbow trout (Oncorhynchus mykiss). Immunogenetics. 2006 Apr;58(2-3):152-67.
  • Kumánovics A, Fischer Lindahl K. Good copy, bad copy: choosing animal models for HLA-linked diseases. Curr Opin Genet Dev. 2004 Jun;14(3):258-63. Review.
  • Amadou C, Younger RM, Sims S, Matthews LH, Rogers J, Kumanovics A, Ziegler A, Beck S, Lindahl KF. Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex. Hum Mol Genet. 2003 Nov 15;12(22):3025-40. Epub 2003 Sep 23.
  • Takada T, Kumánovics A, Amadou C, Yoshino M, Jones EP, Athanasiou M, Evans GA, Fischer Lindahl K. Species-specific class I gene expansions formed the telomeric 1 mb of the mouse major histocompatibility complex. Genome Res. 2003 Apr;13(4):589-600.
  • Loconto J, Papes F, Chang E, Stowers L, Jones EP, Takada T, Kumánovics A, Fischer Lindahl K, Dulac C. Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules. Cell. 2003 Mar 7;112(5):607-18.
  • Kumánovics A, Takada T, Lindahl KF. Genomic organization of the mammalian MHC. Annu Rev Immunol. 2003;21:629-57. Review.
  • Kumánovics A, Madan A, Qin S, Rowen L, Hood L, Fischer Lindahl K. QUOD ERAT FACIENDUM: sequence analysis of the H2-D and H2-Q regions of 129/SvJ mice. Immunogenetics. 2002 Oct;54(7):479-89. Epub 2002 Sep 20.
  • Kumánovics A, Levin G, Blount P. Family ties of gated pores: evolution of the sensor module. FASEB J. 2002 Oct;16(12):1623-9.
  • Kumánovics A, Lindahl KF. G7c in the lung tumor susceptibility (Lts) region of the Mhc class III region encodes a von Willebrand factor type A domain protein. Immunogenetics. 2001 Feb;53(1):64-8.
  • Amadou C, Kumánovics A, Jones EP, Lambracht-Washington D, Yoshino M, Lindahl KF. The mouse major histocompatibility complex: some assembly required. Immunol Rev. 1999 Feb;167:211-21. Review.
  • Jones EP, Kumánovics A, Yoshino M, Fischer Lindahl K. Mhc class I and non-class I gene organization in the proximal H2-M region of the mouse. Immunogenetics. 1999 Mar;49(3):183-95.
  • Balogh P, Kumánovics A, Juhász I. Studies on the tissue-related phenotypic heterogeneity of murine B cells. Dev Immunol. 1998;6(3-4):179-85.
  • Berki T, Kumánovics G, Kumánovics A, Falus A, Ujhelyi E, Németh P. Production and flow cytometric application of a monoclonal anti-glucocorticoid receptor antibody. J Immunol Methods. 1998 May 1;214(1-2):19-27.
  • Yoshino M, Xiao H, Jones EP, Kumánovics A, Amadou C, Fischer Lindahl K. Genomic evolution of the distal Mhc class I region on mouse Chr 17. Hereditas. 1997;127(1-2):141-8.
  • Balogh P, Kumánovics A. Tissue-associated phenotypic heterogeneity of peripheral B cells in mice. Immunology. 1995 Dec;86(4):560-7.

Randy D. Lamb, M.D.

  • Bronson RT, Michaelis DJ, Lamb RD, Husseini GA, Farnsworth PB, Linford MR, Izatt RM, Bradshaw JS, Savage PB. Efficient immobilization of a cadmium chemosensor in a thin film: generation of a cadmium sensor prototype. Org Lett. 2005 Mar 17;7(6):1105-8.
  • Bronson RT, Montalti M, Prodi L, Zaccheroni N, Lamb RD, Dalley, NK, Izatt RM, Bradshaw JS, Savage PB. Origins of 'on-off' fluorescent behavior of 8-hydroxyquinoline containing chemosesors. Tetrahedron. 2004 Nov;60(49): 11139-11144.

Vicky Leventaki, M.D.

  • Cotta CV, Leventaki V, Atsaves V, Vidaki A, Schlette E, Jones D, Medeiros LJ, Rassidakis GZ. The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas. Cancer. 2007 Dec 17.
  • Drakos E, Thomaides A, Medeiros LJ, Li J, Leventaki V, Konopleva M, Andreeff M, Rassidakis GZ. Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma. Clin Cancer Res. 2007 Jun 1;13(11):3380-7.
  • Leventaki V, Drakos E, Medeiros LJ, Lim MS, Elenitoba-Johnson KS, Claret FX, Rassidakis GZ. NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma. Blood. 2007 Sep 1;110(5):1621-30.
  • Drakos E, Leventaki V, Schlette EJ, Jones D, Lin P, Medeiros LJ, Rassidakis GZ. c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders. Am J Surg Pathol. 2007 Mar;31(3):447-53.
  • Drakos E, Rassidakis GZ, Leventaki V, Guo W, Medeiros LJ, Nagarajan L. Differential expression of the human MIXL1 gene product in non-Hodgkin and Hodgkin lymphomas. Hum Pathol. 2007 Mar;38(3):500-7.
  • Peponi E, Drakos E, Reyes G, Leventaki V, Rassidakis GZ, Medeiros LJ. Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma. Am J Pathol. 2006 Dec;169(6):2171-80.
  • Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res. 2006 Jul 1;66(13):6589-97.
  • Oyarzo MP, Medeiros LJ, Atwell C, Feretzaki M, Leventaki V, Drakos E, Amin HM, Rassidakis GZ. c-FLIP confers resistance to FAS-mediated apoptosis in anaplastic large-cell lymphoma. Blood. 2006 Mar 15;107(6):2544-7.
  • Lai R, Leventaki V, Rassidakis GZ. Rust et al. TIMP-1 expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells. J Pathol 2005;206:445-450. J Pathol. 2005 Nov;207(3):372-3; author reply 374-5.
  • Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene. 2004 Jul 15;23(32):5426-34.
  • Khoury JD, Medeiros LJ, Rassidakis GZ, Yared MA, Tsioli P, Leventaki V, Schmitt-Graeff A, Herling M, Amin HM, Lai R. Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma. Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3692-9.
  • Amin HM, Medeiros LJ, Ma Y, Feretzaki M, Das P, Leventaki V, Rassidakis GZ, O'Connor SL, McDonnell TJ, Lai R. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma. Oncogene. 2003 Aug 21;22(35):5399-407.
  • Amin HM, McDonnell TJ, Medeiros LJ, Rassidakis GZ, Leventaki V, O'Connor SL, Keating MJ, Lai R. Characterization of 4 mantle cell lymphoma cell lines. Arch Pathol Lab Med. 2003 Apr;127(4):424-31.
  • Lai R, Rassidakis GZ, Medeiros LJ, Leventaki V, Keating M, McDonnell TJ. Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours. J Pathol. 2003 Jan;199(1):84-9.

Gloria H. Lewis, M.D.

  • Barnholtz, SL, Lydon JD, Huang G, Venkatesh M, Barnes CL, Ketring AR, Jurisson SS. Syntheses and Characterization of Gold(III) Tetradentate Schiff Base Complexes. X-ray Crystal Structures of [Au(sal2pn)]C12 5H2O and [Au(sal2en)]PF6. Inorganic Chemistry. 2001 Jan; 40(5): 972-976.

Jay L. Patel, M.D.

  • Stea B, Falsey R, Kislin K, Patel J, Glanzberg H, Carey S, Ambrad AA, Meuillet EJ, Martinez JD. Time and dose-dependent radiosensitization of the glioblastoma multiforme U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa'). Cancer Lett. 2003 Dec 8;202(1):43-51.

Nikhil A. Sangle, M.D.

  • Amarapurkar AD, Sangle N, Pandya JS, Jain A. Unusual histological variant of giant cell gall bladder carcinoma. J Postgrad Med. 2005 Apr-Jun;51(2):133-4.
  • Amarapurkar AD, Sangle NA. Histological spectrum of liver in HIV - autopsy study. Ann Hepatol. 2005 Jan-Mar;4(1):47-51.
  • Salkade H, Sangle NA. Gaucher like cells in spleen in Thalassemia major, Bombay Hospital Journal, 2005 Jan; 47(1): 61-62.

Brian H. Shirts, M.D., Ph.D.

  • Handler SM, Shirts BH, Perera S, Becich MJ, Castle NG, Hanlon JT. Frequency of laboratory monitoring of chronic medications administered to nursing facility residents: results of a national internet-based study. Consult Pharm. 2008 May;23(5):387-95.
  • Shirts BH, Wood J, Yolken RH, Nimgaonkar VL. Comprehensive evaluation of positional candidates in the IL-18 pathway reveals suggestive associations with schizophrenia and herpes virus seropositivity. Am J Med Genet B Neuropsychiatr Genet. 2008 Apr 5;147(3):343-50.
  • Talkowski ME, Kirov G, Bamne M, Georgieva L, Torres G, Mansour H, Chowdari KV, Milanova V, Wood J, McClain L, Prasad K, Shirts B, Zhang J, O'Donovan MC, Owen MJ, Devlin B, Nimgaonkar VL. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet. 2008 Mar 1;17(5):747-58.
  • Shirts BH, Kim JJ, Reich S, Dickerson FB, Yolken RH, Devlin B, Nimgaonkar VL. Polymorphisms in MICB are associated with human herpes virus seropositivity and schizophrenia risk. Schizophr Res. 2007 Aug;94(1-3):342-53.
  • Kim JJ, Shirts BH, Dayal M, Bacanu SA, Wood J, Xie W, Zhang X, Chowdari KV, Yolken R, Devlin B, Nimgaonkar VL. Are exposure to cytomegalovirus and genetic variation on chromosome 6p joint risk factors for schizophrenia? Ann Med. 2007;39(2):145-53.
  • Prasad KM, Shirts BH, Yolken RH, Keshavan MS, Nimgaonkar VL. Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia. Mol Psychiatry. 2007 Jan;12(1):105-13, 1.
  • Shirts BH, Wood J, Yolken RH, Nimgaonkar VL. Association study of IL10, IL1beta, and IL1RN and schizophrenia using tag SNPs from a comprehensive database: suggestive association with rs16944 at IL1beta. Schizophr Res. 2006 Dec;88(1-3):235-44.
  • Shirts BH, Bamne M, Kim JJ, Talkowski M, Wood J, Yolken R, Nimgaonkar VL. A comprehensive genetic association and functional study of TNF in schizophrenia risk. Schizophr Res. 2006 Mar;83(1):7-13.
  • Shirts BH, Nimgaonkar V. The genes for schizophrenia: finally a breakthrough? Curr Psychiatry Rep. 2004 Aug;6(4):303-12. Review.
  • Hart TC, Gorry MC, Hart PS, Woodard AS, Shihabi Z, Sandhu J, Shirts B, Xu L, Zhu H, Barmada MM, Bleyer AJ. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet. 2002 Dec;39(12):882-92.
  • Howard MT, Shirts BH, Zhou J, Carlson CL, Matsufuji S, Gesteland RF, Weeks RS, Atkins JF. Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes. Genes Cells. 2001 Nov;6(11):931-41.
  • Howard MT, Shirts BH, Petros LM, Flanigan KM, Gesteland RF, Atkins JF. Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy. Ann Neurol. 2000 Aug;48(2):164-9.

Christopher M. Sjostrom, M.D.

  • Sjostrom C, Seiler C, Crockett DK, Tripp SR, Elenitoba Johnson KS, Lim MS. Global proteome profiling of NPM/ALK-positive anaplastic large cell lymphoma. Exp Hematol. 2007 Aug;35(8):1240-8.
  • Houlne MP, Sjostrom CM, Uibel RH, Kleimeyer JA, Harris JM. Confocal Raman microscopy for monitoring chemical reactions on single optically trapped, solid-phase support particles. Anal Chem. 2002 Sep 1;74(17):4311-9.

Silvia Skripenova, M.D.

  • Layfield LJ, Skripenova S, Bentz J, Smock C. Cytologic fine needle aspiration findings by vegetant intravascular hemangioendothelioma. Acta Cytol. 2008 Mar-Apr;52(2):273-5.
  • Skripenova S, Trainer TD, Krawitt EL, Blaszyk H. Variability of grade and stage in simultaneous paired liver biopsies in patients with hepatitis C. J Clin Pathol. 2007 Mar;60(3):321-4.

Carolin J. Teman, M.D.

  • Yu X, Minter-Dykhouse K, Malureanu L, Zhao WM, Zhang D, Merkle CJ, Ward IM, Saya H, Fang G, van Deursen J, Chen J. Chfr is required for tumor suppression and Aurora A regulation. Nat Genet. 2005 Apr;37(4):401-6.
  • Merkle CJ, Karnitz LM, Henry-Sanchez JT, Chen J. Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment. J Biol Chem. 2003 Aug 8;278(32):30051-6.
  • Meek LR, Schrump SE, Smith DA, Schulz KM, Dittel PL, Merkle CJ. Female meadow voles housed in long and short daylengths respond to exogenous estrogen with similar mating latencies. Physiol Behav. 2001 May;73(1-2):121-4.
  • Reinholz MM, Merkle CM, Poduslo JF. Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis. Exp Neurol. 1999 Sep;159(1):204-16.

Jeremy C. Wallentine, M.D.

  • Wallentine JC, Kim KK, Iii CE, Vaughn CP, Crockett DK, Tripp SR, Elenitoba-Johnson KS, Lim MS. Comprehensive identification of proteins in Hodgkin lymphoma-derived Reed-Sternberg cells by LC-MS/MS. Lab Invest. 2007 Sep 17