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Brian H. Shirts, M.D., Ph.D. - Pathology Resident
Brian Shirts, M.D., Ph.D.
Rank: PGY- 2
Residency Program: CP-Only
Professional Education
- 2008, M.D. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
- 2006, Ph.D. Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania
- 2001, B.A. Biology, University of Utah, Salt Lake City, Utah
Presentations
- Pilot study of linking web-based supplemental interpretive information to laboratory test reports, Poster, 2009 American Society of Clinical Pathology (ASCP) Annual Meeting, Chicago, Illinois, October 29, 2009
- Changing interpretations, stable genes - Responsibilities of patients, professionals, and policy makers in the clinical interpretations of complex genetic information, Poster, Cold Springs Harbor Laboratory Personal Genomes Meeting, Cold Springs Harbor, New York, October, 2008
- Comprehensive evaluation of positional candidates in the IL-18 pathway reveals suggestive associations with schizophrenia and herpes virus seropositivity, suggesting possible gene-environment interaction, Poster, Cold Springs Harbor Laboratory Biology of Genomes Meeting, Cold Springs Harbor, New York, May, 2007
- Pleiotropic effects of polymorphisms in MICB on human herpes virus seroposivity and schizophrenia risk, Poster, American Society of Human Genetics, New Orleans, Louisiana, October, 2006
- Analysis of the dopamine hypothesis in schizophrenia reveals significant main effects and interactions between the dopamine transporter ad dopamine D3 receptor genes, Poster, American Society of Human Genetics, New Orleans, Louisiana, October, 2006
- A comprehensive genetic association and functional study of TNF in schizophrenia risk, Poster, American Society of Human Genetics, Salt Lake City, Utah, October, 2005
- Exposure to Cytomegalovirus and polymorphisms in two genes on chromosome 6p21-23 as joint risk factors for schizophrenia, Poster, International Congress on Psychiatric Genetics, Dublin, Ireland, October, 2004
- Joint Risk Due to Chromosome 6p Variation and Exposure to CMV in Schizophrenia Susceptibility?, Poster, American Society of Human Genetics, Toronto, Ontario, Canada, October, 2004
Publications
- Shirts BH, Gundlapalli AV, Jackson BR. Pilot Study of Linking Web-Based Supplemental Interpretive Information to Laboratory Test Reports. Am J Clin Pathol. 2009 Dec;132(6):818-823.
- Shirts BH, Perera S, Hanlon JT, Roumani YF, Studenski SA, Nace DA, Becich MJ, Handler SM. Provider Management of and Satisfaction With Laboratory Testing in the Nursing Home Setting: Results of a National Internet-Based Study. Journal of the American Medical Directors Association. 2009 Mar;10(3):161-166.e3.
- Shirts BH, Parker LS. Changing interpretations, stable genes: responsibilities of patients, professionals, and policy makers in the clinical interpretation of complex genetic information. Genet Med. 2008 Nov;10(11):778-83.
- Shirts BH, Prasad KM, Pogue-Geile MF, Dickerson F, Yolken RH, Nimgaonkar VL. Antibodies to cytomegalovirus and Herpes Simplex Virus 1 associated with cognitive function in schizophrenia. Schizophr Res. 2008 Dec;106(2-3):268-74.
- Handler SM, Shirts BH, Perera S, Becich MJ, Castle NG, Hanlon JT. Frequency of laboratory monitoring of chronic medications administered to nursing facility residents: results of a national internet-based study. Consult Pharm. 2008 May;23(5):387-95.
- Shirts BH, Wood J, Yolken RH, Nimgaonkar VL. Comprehensive evaluation of positional candidates in the IL-18 pathway reveals suggestive associations with schizophrenia and herpes virus seropositivity. Am J Med Genet B Neuropsychiatr Genet. 2008 Apr 5;147(3):343-50.
- Talkowski ME, Kirov G, Bamne M, Georgieva L, Torres G, Mansour H, Chowdari KV, Milanova V, Wood J, McClain L, Prasad K, Shirts B, Zhang J, O'Donovan MC, Owen MJ, Devlin B, Nimgaonkar VL. A network of dopaminergic gene variations implicated as risk factors for schizophrenia. Hum Mol Genet. 2008 Mar 1;17(5):747-58.
- Shirts BH, Kim JJ, Reich S, Dickerson FB, Yolken RH, Devlin B, Nimgaonkar VL. Polymorphisms in MICB are associated with human herpes virus seropositivity and schizophrenia risk. Schizophr Res. 2007 Aug;94(1-3):342-53.
- Kim JJ, Shirts BH, Dayal M, Bacanu SA, Wood J, Xie W, Zhang X, Chowdari KV, Yolken R, Devlin B, Nimgaonkar VL. Are exposure to cytomegalovirus and genetic variation on chromosome 6p joint risk factors for schizophrenia? Ann Med. 2007;39(2):145-53.
- Prasad KM, Shirts BH, Yolken RH, Keshavan MS, Nimgaonkar VL. Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia. Mol Psychiatry. 2007 Jan;12(1):105-13, 1.
- Shirts BH, Wood J, Yolken RH, Nimgaonkar VL. Association study of IL10, IL1beta, and IL1RN and schizophrenia using tag SNPs from a comprehensive database: suggestive association with rs16944 at IL1beta. Schizophr Res. 2006 Dec;88(1-3):235-44.
- Shirts BH, Bamne M, Kim JJ, Talkowski M, Wood J, Yolken R, Nimgaonkar VL. A comprehensive genetic association and functional study of TNF in schizophrenia risk. Schizophr Res. 2006 Mar;83(1):7-13.
- Shirts BH, Nimgaonkar V. The genes for schizophrenia: finally a breakthrough? Curr Psychiatry Rep. 2004 Aug;6(4):303-12. Review.
- Hart TC, Gorry MC, Hart PS, Woodard AS, Shihabi Z, Sandhu J, Shirts B, Xu L, Zhu H, Barmada MM, Bleyer AJ. Mutations of the UMOD gene are responsible for medullary cystic kidney disease 2 and familial juvenile hyperuricaemic nephropathy. J Med Genet. 2002 Dec;39(12):882-92.
- Howard MT, Shirts BH, Zhou J, Carlson CL, Matsufuji S, Gesteland RF, Weeks RS, Atkins JF. Cell culture analysis of the regulatory frameshift event required for the expression of mammalian antizymes. Genes Cells. 2001 Nov;6(11):931-41.
- Howard MT, Shirts BH, Petros LM, Flanigan KM, Gesteland RF, Atkins JF. Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy. Ann Neurol. 2000 Aug;48(2):164-9.