Department: Pharmaceutics & Bioengineering

E-mail: hamid.ghandehari@pharm.utah.edu
Address: 383 Colorow Drive, Room 343
Phone: 587-1566

Research Title: Genetically engineered polymers for gene delivery

Description of Research:

Recombinant DNA technology has enabled the synthesis of protein-based polymers with precisely controlled structures. Control over polymer structure at the molecular level has important implications for controlled delivery applications. The potential of recombinant silk-elastinlike protein polymers (SELPs) for matrix-mediated gene delivery is being explored. The idea is that by using recombinant techniques it is possible to systematically correlate polymer structure with gene release and transfer. Our main focus is on gene therapy applications in the treatment of head and neck cancer.

Does this research involve human subjects or animals? Yes

If yes, what is the protocol number? 08-04007, 08-11018, 08-12006, 08-0014, IRB-00036708

11/2009