Department: Pharmaceutics & Engineering

E-mail: hamid.ghandehari@pharm.utah.edu
Address: 383 Colorow Drive, Room 343
Phone: 587-1566

Research Title: Water-soluble polymers for targeted delivery

Description of Research:

Targeted delivery of bioactive agents by water soluble polymers can increase efficacy and reduce toxicity. The synthesis, characterization and biological evaluation of targetable N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery to angiogenic blood vessels of solid tumors are being investigated. By tailor-making the size and charge of these copolymers it is possible to alter biodistribution and minimize uptake by nontarget organs. Similar polymeric systems have been evaluated for targeted delivery of antileishmanial and magnetic resonance contrast agents.

Does this research involve human subjects or animals? Yes

Does this research involve human subjects or animals? Yes

If yes, what is the protocol number? 08-04007, 08-11018, 08-12006, 08-0014, IRB-00036708

11/2009