John Weis - Researchers Show Gene Variation Associated with Rare Heart Problem in Children

Scientists from the University of Utah School of Medicine are the first to show that a genetic variation in the IFITM3 gene is associated with a higher risk of developing coronary artery lesions in patients with Kawasaki disease–regarded as the leading cause of acquired heart disease among children in developed countries. This new finding, published in the May 13, 2014, issue of Molecular Genetics & Genomic Medicine, gives insight into potential mechanisms for Kawasaki disease and provides further evidence that viruses may play an important role in development of this inflammatory condition.

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John Weis - Researchers Show Gene Variation Associated with Rare Heart Problem in Children

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The Department of Pathology is dedicated to understanding the basis of disease, to teach knowledge to others, and to apply our understanding to improve medical diagnoses and treatment of patients.

Dr. Jensen, Chair, Department of Pathology

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Research

The research goal in the Department of Pathology is to extend our knowledge of the mechanisms of disease, especially at the molecular level. Such detailed information will hopefully lead to improved diagnoses, treatment, and eventually, prevention.