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Research Labs
Up one levelBasic research in the Department of Pathology includes programs in molecular and cellular immunology, microbial pathogenesis, autoimmunity, gene regulation, hematopoiesis, vesicular trafficking, and iron transport.
Sherwood Casjens' Lab
The Casjens laboratory is studying the genetic control of the assembly and function of virus particles, the modular evolution of bacteriophage genomes, and the genome structure, replication and diversity of the Lyme disease causing bacteria, Borrelia burgdorferi.
Xinjian Chen's Lab
We study how our immune system discriminate infectious non-self from self so that it can specifically react against invasions of infectious microorganisms but keep non-reactive towards self-components.
Ray Daynes' Lab
The research efforts of my laboratory are focused on understanding the molecular processes that collectively serve to regulate various cellular components of the mammalian immune system. Specifically, we research the roles played by a number of steroid hormones and their cellular receptors in controlling the initiation, types, magnitude and duration of innate and adaptive immune responses in vivo.
Julio Delgado's Lab
The focus of our research is to understand the functional role of the HLA system in the setting of transplantation and susceptibility to disease.
David Eckels' Lab
The Histocompatibility and Immunogenetics Laboratory provides a complete range of diagnostic testing services used primarily in the field of clinical organ transplantation and for study of associations between certain diseases and several HLA alloantigens.
HCI Research Labs
The collaborative research approach between doctors and scientists, with an emphasis on investigating the genetic basis of cancer, makes Huntsman Cancer Institute one of the leading cancer research organizations in the country.
Xiao He's Lab
We are interested in identifying, characterizing the genes, which regulate the functions of T lymphocytes, and ultimately applying the new findings to improve diagnosis and treatment of related human diseases.
Joe Holden's Lab
My research involves identifying and characterizing altered tyrosine kinases in human tumors.
Wai Mun Huang's Lab
My laboratory studies the mechanism of dynamic protein-DNA interactions with emphasis on those that changes DNA conformations.
Peter Jensen's Lab
The Jensen laboratory is focused on antigen processing and presentation, and the role of classical and nonclassical histocompatibility (MHC) molecules in regulating immune responses.
Jerry Kaplan's Lab
Our research focuses on two topics, iron metabolism specifically compartmentalization and utilization and membrane trafficking and the regulation of endocytic vesicle size.
Todd Kelley's Lab
Identification of new prognostic markers and therapeutic targets in lymphoma and leukemia.
Matt Mulvey's Lab
We wish to define how strains or uropathogenic Escherichia coli (UPEC) and related bacterial pathogens colonize host tissues and persist in the face of numerous innate and adaptive defenses.
Vicente Planelles' Lab
Pathogenesis by the human immunodeficiency virus: how HIV induces alterations in the cell cycle of the host cells, leading to programmed cell death.
Ila Singh's Laboratory
Our research interests involve many aspects of retroviral replication. We study HIV-1, Moloney murine leukemia virus, and XMRV, a novel xenotropic murine-like retrovirus that has recently been implicated in human prostate cancer.
David Stillman's Lab
We study molecular mechanisms controlling eukaryotic transcriptional regulation, using the powerful genetic and molecular tools available in Saccharomyces. Findings are universal, as the transcription machinery is conserved between yeast and vertebrates.
Dean Tantin's Lab
Our laboratory is interested in the mechanisms by which gene expression is controlled in mammals, and the physiological consequences of disruption of these pathways--for example in cancer and immune dysfunction.
Janis Weis' Lab
We are interested in characterization of the inflammatory pathways involved in the development of Lyme arthritis, as a model for regulation of inflammatory pathologies.
John Weis' Lab
Our laboratory studies the interfaces between the innate and acquired immune responses. We take a genetics approach, using the mouse as a model system, to decipher molecular and cellular interactions.
Matthew Williams Lab
The research of my lab is focused on the mechanisms driving the development of long-lived immunological memory following bacterial or viral infection.
Carl Wittwer's Lab
We develop simple techniques to analyze DNA, including methods, instruments and software necessary for rapid-cycle amplification, real-time monitoring, and high-resolution DNA melting analysis.